Synthesis and antimicrobial activities of 2-substituted 12H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidines, 3-ethoxycarbonyl-12H-chromeno[3,2-e][1,2,4]triazolo[1,5-c] pyrimidine-2-one and ethyl 2-formylamino- and 2-acetylamino-4H-chromene-3-carboxylates

Author:

El-Agrody Ahmed M.1,Sabry Nermien M.2,Motlaq Shymaa S.2

Affiliation:

1. Chemistry Department, Faculty of Science, King Khalid University, 9004, Abha, Saudi Arabia

2. Chemistry Department, Girls College of Education, King Khalid University, Abha, Saudi Arabia

Abstract

Preparation of 2-substituted 9-(diethylamino)-12-(4-chlorophenyl)-12 H-chromeno[3,2- e][1,2,4]triazolo[1,5- c]pyrimidines is reported. Furthermore, 3-benzylideneamino-5-(4-chlorophenyl)-8-(diethylamino)-4-imino-3,4-dihydro-5 H-chromeno[2,3- d]pyrimidine, 3-ethoxycarbonyl-12 H-chromeno[3,2- e][1,2,4]triazolo[1,5- c]pyrimidine-2-one, ethyl 2-formylamino- and 2-acetylamino-4 H-chromene-3-carboxylates were prepared. Structures of these compounds were established on the basis of IR, UV, 1H NMR, 13C NMR and MS data. The new compounds were evaluated for antimicrobial activities.

Publisher

SAGE Publications

Subject

General Chemistry

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