Synthesis of Quinolino[2′,3′:7,6]Cyclohept[b]Indoles and their Antimicrobial Activities-Reference-Cited by-同舟云学术

Synthesis of Quinolino[2′,3′:7,6]Cyclohept[b]Indoles and their Antimicrobial Activities

Published:2010-07 Issue:7 Volume:34 Page:385-389
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Yamuna Ezhumalai¹,Prasad Karnam Jayarampillai Rajendra¹

Affiliation:

1. Department of Chemistry, Bharathiar University, Coimbatore- 641 046, Tamil Nadu, India

Abstract

Practicable and concise syntheses of 6-chloro-7,8,9,14-tetrahydroquinolino[2′,3′:7,6]cyclohept[b]indoles by two routes are described. Both commenced with 1-oxo-2,3,4,5,10-hexahydrocyclohept[b]indoles and utilised either the acid-catalysed condensation with 2-aminobenzonitrile, followed by treatment with POCl3 or, better, direct condensation of the ketone with anthranilic acid in POCl3.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823410X520769

Reference24 articles.

1. Structure Determination and Synthesis of Fluoro Nissl Green: An RNA-Binding Fluorochrome

2. Reactions of 3-([(trifluoromethyl)sulfonyl]oxy)-1H-indole derivatives with diamines and carbon nucleophiles. Synthesis of 6H-indolo[2,3-b]quinoxaline derivatives

3. A simple and practical approach to the synthesis of the marine sponge pigment fascaplysin and related compounds

4. A new approach to the synthesis of functionalized pyrido[2,3-b]indoles by way of a palladium-catalyzed ring closing reaction between the N-1 and C-9a positions

5. Alkaloids from the Tunicate Polycarpa aurata from Chuuk Atoll

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