Four-Component Reaction between Cyclohexyl Isocyanide, Aromatic Aldehydes, Aromatic Amines and Trifluoroacetic Anhydride-Reference-Cited by-同舟云学术

Four-Component Reaction between Cyclohexyl Isocyanide, Aromatic Aldehydes, Aromatic Amines and Trifluoroacetic Anhydride

Published:2010-05 Issue:5 Volume:34 Page:259-262
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Anary-Abbasinejad Mohammad¹²,Anaraki-Ardakani Hossein³,Rasekh Maryam²,Tabatabaee Masoumeh²,Nazari Ali⁴

Affiliation:

1. Yong Research Club, Islamic Azad University, Anar Branch, Anar, Iran

2. Department of Chemistry, Islamic Azad University, Yazd Branch, PO Box 89195-155, Yazd, Iran

3. Department of Chemistry, Islamic Azad University, Mahshahr Branch, P.O. Box 63519,Mahshahr, Iran

4. Fabric and Cloth Design Group, Islamic Azad University, Yazd Branch, PO Box: 89195-155, Yazd, Iran

Abstract

Reaction of cyclohexyl isocyanide with aromatic aldehydes, aniline derivatives and trifluoroacetic anhydride in dichloromethane at room temperature afforded N-[cyclohexylcarbamoyl(aryl)methyl]-2,2,2-trifluoro-N-arylacetamide derivatives in nearly quantitative yields after 10 min. The work-up procedure is very easy and the products are precipitated in ether as pure solids. The structure of one of the products was established by X-ray single crystal analysis.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823410X12733989345690

Reference23 articles.

1. Tandem Reaction Sequences under Hydroformylation Conditions: New Synthetic Applications of Transition Metal Catalysis

2. Recent progress in the chemistry of multicomponent reactions

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