1. 1UCIBIO, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto. Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal
2. Department of Chemical Sciences, Laboratory of Organic and Pharmaceutical Chemistry, Faculty of Pharmacy, University of Porto. Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal
3. Department of Public Health and Forensic Sciences, and Medical Education, Faculty of Medicine, University of Porto, Porto, Portugal, Prof. Hernâni Monteiro Alameda, 4200-319 Porto, Portugal
4. IINFACTS - Institute of Research and Advanced Training in Health Sciences and Technologies, Department of Sciences, University Institute of Health Sciences (IUCS), CESPU, CRL, Central de Gandra Street, 1317, 4585-116 Gandra, PRD, Gandra, Portugal