OxLDL-derived lysophosphatidic acid promotes the progression of aortic valve stenosis through a LPAR1-RhoA–NF-κB pathway-Reference-Cited by-同舟云学术

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OxLDL-derived lysophosphatidic acid promotes the progression of aortic valve stenosis through a LPAR1-RhoA–NF-κB pathway

Published:2017-05-04 Issue:11 Volume:113 Page:1351-1363
ISSN:0008-6363
Container-title:Cardiovascular Research
language:en
Short-container-title:

Author:

Nsaibia Mohamed Jalloul¹,Boulanger Marie-Chloé¹,Bouchareb Rihab¹,Mkannez Ghada¹,Le Quang Khai¹,Hadji Fayez¹,Argaud Deborah¹,Dahou Abdellaziz²,Bossé Yohan²,Koschinsky Marlys L.³,Pibarot Philippe²,Arsenault Benoit J.²,Marette André²,Mathieu Patrick¹

Affiliation:

1. Laboratory of Cardiovascular Pathobiology, Institut Universitaire de Cardiologie et de Pneumologie de Québec/Quebec Heart and Lung Institute, Research Center, Department of Surgery, Laval University, 2725 Chemin Ste-Foy, Quebec, Quebec G1V-4G5, Canada;

2. Institut Universitaire de Cardiologie et de Pneumologie de Québec/Quebec Heart and Lung Institute, Research Center, Laval University, Quebec, Canada;

3. Western University, 1151 Richmond St, London N6A-5B7, Ontario, Canada

Funder

CIHR

Heart and Stroke Foundation of Canada

FRQS

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Link

http://academic.oup.com/cardiovascres/article-pdf/113/11/1351/24254055/cvx089.pdf

Reference38 articles.

1. Calcific aortic valve disease: not simply a degenerative process: a review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: calcific aortic valve disease-2011 update;Rajamannan;Circulation,2011

2. Valvular osteoclasts in calcification and aortic valve stenosis severity;Nagy;Int J Cardiol,2013

3. Innate and adaptive immunity in calcific aortic valve disease;Mathieu;J Immunol Res,2015

4. Gene-specific repression of proinflammatory cytokines in stimulated human macrophages by nuclear IkappaBalpha;Ghosh;J Immunol,2010

5. Site-specific phosphorylation of the p65 protein subunit mediates selective gene expression by differential NF-kappaB and RNA polymerase II promoter recruitment;Hochrainer;J Biol Chem,2013

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1. Lysophosphatidic acid metabolism and signaling in heart disease;Canadian Journal of Physiology and Pharmacology;2024-07-05

2. Autotaxin inhibition attenuates the aortic valve calcification by suppressing inflammation-driven fibro-calcific remodeling of valvular interstitial cells;BMC Medicine;2024-03-14

3. Major Facilitator Superfamily Domain Containing 5 Inhibition Reduces Lipoprotein(a) Uptake and Calcification in Valvular Heart Disease;Circulation;2024-01-30

4. Vascular calcification and cellular signaling pathways as potential therapeutic targets;Life Sciences;2024-01

5. Identification of oxidative stress-related genes associated with immune cells in Aortic Valve Stenosis based on bioinformatics analysis;Cellular and Molecular Biology;2023-12-31

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