A retrospective single-centre case series of paediatric blistering severe cutaneous adverse reactions: evaluation using new diagnostic classification confirms value of British Association of Dermatologists’ guidelines

Abstract

Stevens–Johnson syndrome and toxic epidermal necrolysis are especially challenging to diagnose and manage in paediatric populations given their rarity, more frequent infectious triggers and lack of randomized controlled trials to guide management. This retrospective case series of 59 paediatric blistering severe cutaneous adverse reactions uses the new diagnostic classification and British Association of Dermatologists’ guidelines, and confirms their value in a real-life clinical setting.