The Persistence of Underreporting of Hepatitis C as an Underlying or Contributing Cause of Death, 2011–2017

Author:

Spradling Philip R1,Zhong Yuna1,Moorman Anne C1,Rupp Loralee B2,Lu Mei2,Teshale Eyasu H1,Schmidt Mark A3,Daida Yihe G4,Boscarino Joseph A5,Gordon Stuart C26,Teshale Eyasu H,Spradling Philip R,Moorman Anne C,Xing Jian,Zhong Yuna,Gordon Stuart C,Lu Mei,Li Jia,Rupp Loralee B,Akkerman Nonna,Trudeau Sheri,Zhou Yueren,Boscarino Joseph A,Daar Zahra S,Smith Robert E,Daida Yihe G,Trinacty Connie Mah,Lai Jonathan W,Nie Sixiang,Wong Carmen P,Schmidt Mark A,Donald Judy L,

Affiliation:

1. Division of Viral Hepatitis, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA

2. Henry Ford Health System, Detroit, Michigan, USA

3. The Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA

4. The Center for Integrated Health Research, Kaiser Permanente Hawaii, Honolulu, Hawaii, USA

5. Department of Population Health Sciences, Geisinger Clinic, Danville, Pennsylvania, USA

6. Wayne State University School of Medicine, Detroit, Michigan, USA

Abstract

Abstract Using electronic health records, we found that hepatitis C virus (HCV) reporting on death certificates of 2901 HCV-infected decedents from 4 US healthcare organizations during 2011–2017 was documented in only 50% of decedents with hepatocellular carcinoma and less than half with decompensated cirrhosis. National figures likely underestimate the US HCV mortality burden.

Funder

Gilead Sciences

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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