Coronavirus Disease 2019 Symptoms and Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Positivity in a Large Survey of First Responders and Healthcare Personnel, May–July 2020

Author:

Akinbami Lara J12ORCID,Petersen Lyle R3,Sami Samira45,Vuong Nga5,Lukacs Susan L12,Mackey Lisa3,Atas Jenny6,LaFleur Bonnie J7

Affiliation:

1. National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland, USA

2. US Public Health Service, Rockville, Maryland, USA

3. National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA

4. Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

5. National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

6. Region 2 South Healthcare Coalition, Detroit, Michigan, USA

7. BIO5 Institute, University of Arizona, Tucson, Arizona, USA

Abstract

Abstract A severe acute respiratory syndrome coronavirus 2 serosurvey among first responder/healthcare personnel showed that loss of taste/smell was most predictive of seropositivity; percent seropositivity increased with number of coronavirus disease 2019 symptoms. However, 22.9% with 9 symptoms were seronegative, and 8.3% with no symptoms were seropositive. These findings demonstrate limitations of symptom-based surveillance and importance of testing.

Funder

U.S. Department of Health and Human Services

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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