Severe Hypoxemia With Normal Heart and Respiratory Rate in Early-stage Coronavirus Disease 2019 Patients: The “Happy Hypoxemia Phenomenon”

Author:

Safe Izabella Picinin1,Lacerda Marcus Vinícius Guimarães123,Almeida Val Fernando Fonseca1,Sampaio Vanderson Souza14,Hajjar Ludhmila Abrahão5,Brito-Sousa Jose Diego2,Baía-da-Silva Djane2,Bassat Quique678910,Landoni Giovanni1112,Monteiro Wuelton Marcelo12

Affiliation:

1. Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil

2. Universidade do Estado do Amazonas, Manaus, Brazil

3. Instituto Leônidas & Maria Deane, Fiocruz Amazonas, Manaus, Brazil

4. Fundação de Vigilância em Saúde do Amazonas; Manaus, Brazil

5. Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

6. ISGlobal, Hospital Clínic–Universitat de Barcelona, Barcelona, Spain

7. Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique

8. ICREA, Barcelona, Spain

9. Pediatric Infectious Diseases Unit, Pediatrics Department, Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain

10. Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain

11. Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy

12. Vita-Salute San Raffaele University, Milan, Italy

Funder

Fundação de Amparo à Pesquisa do Estado do Amazonas

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Reference10 articles.

1. The pathophysiology of “happy” hypoxemia in COVID-19;Dhont;Respir Res,2020

2. Association between hypoxemia and mortality in patients with COVID-19;Xie;Mayo Clin Proc,2020

3. Progressive hypoxia: a pivotal pathophysiologic mechanism of COVID-19 pneumonia;Somers;Mayo Clin Proc,2020

4. Considerations for target oxygen saturation in COVID-19 patients: are we under-shooting?;Shenoy;BMC Med,2020

5. Dexamethasone in hospitalized patients with Covid-19—preliminary report;Horby;N Engl J Med,2020

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