Severity, criticality, and fatality of the SARS-CoV-2 Beta variant

Author:

Abu-Raddad Laith J1234,Chemaitelly Hiam12,Ayoub Houssein H5,Yassine Hadi M67,Benslimane Fatiha M67,Al Khatib Hebah A67,Tang Patrick8,Hasan Mohammad R8,Coyle Peter6910,AlMukdad Sawsan12,Al Kanaani Zaina9,Al Kuwari Einas9,Jeremijenko Andrew9,Kaleeckal Anvar Hassan9,Latif Ali Nizar9,Shaik Riyazuddin Mohammad9,Abdul Rahim Hanan F4,Nasrallah Gheyath K67,Al Kuwari Mohamed Ghaith11,Butt Adeel A39,Al Romaihi Hamad Eid12,Al-Thani Mohamed H12,Al Khal Abdullatif9,Bertollini Roberto12

Affiliation:

1. Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University, Qatar Foundation – Education City, Doha, Qatar

2. World Health Organization Collaborating Centre for Disease Epidemiology Analytics on HIV/AIDS, Sexually Transmitted Infections, and Viral Hepatitis, Weill Cornell Medicine–Qatar, Cornell University, Qatar Foundation – Education City, Doha, Qatar

3. Department of Population Health Sciences, Weill Cornell Medicine, Cornell University, New York, New York, USA

4. Department of Public Health, College of Health Sciences, Member of QU Health, Qatar University, Doha, Qatar

5. Mathematics Program, Department of Mathematics, Statistics, and Physics, College of Arts and Sciences, Qatar University; Doha, Qatar

6. Biomedical Research Center, Member of QU Health, Qatar University, Doha, Qatar

7. Department of Biomedical Science, College of Health Sciences, Member of QU Health, Qatar University, Doha, Qatar

8. Department of Pathology, Sidra Medicine, Doha, Qatar

9. Hamad Medical Corporation, Doha, Qatar

10. Wellcome-Wolfson Institute for Experimental Medicine, Queens University, Belfast, United Kingdom

11. Primary Health Care Corporation, Doha, Qatar

12. Ministry of Public Health, Doha, Qatar

Abstract

Abstract Beta (B.1.351) variant COVID-19 disease was investigated in Qatar. Compared to Alpha (B.1.1.7) variant, odds of progressing to severe disease were 1.24-fold (95% CI: 1.11-1.39) higher for Beta. Odds of progressing to critical disease were 1.49-fold (95% CI: 1.13-1.97) higher. Odds of COVID-19 death were 1.57-fold (95% CI: 1.03-2.43) higher.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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