A phase I dose escalation study of oral c-MET inhibitor tivantinib (ARQ 197) in combination with gemcitabine in patients with solid tumors
Author:
Publisher
Elsevier BV
Subject
Oncology,Hematology
Link
http://academic.oup.com/annonc/article-pdf/25/7/1416/24064685/mdu157.pdf
Reference22 articles.
1. Targeting the HGF/Met signaling pathway in cancer therapy;Cecchi;Expert Opin Ther Targets,2012
2. Targeting MET in cancer: rationale and progress;Gherardi;Nat Rev Cancer,2012
3. Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients;Cappuzzo;J Clin Oncol,2009
4. c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases;Zeng;Cancer Lett,2008
5. ARQ 197, a novel and selective inhibitor of the human c-Met receptor tyrosine kinase with antitumor activity;Munshi;Mol Cancer Ther,2010
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