Biomarkers of response and resistance to PI3K inhibitors in estrogen receptor-positive breast cancer patients and combination therapies involving PI3K inhibitors
Author:
Funder
European Society for Medical Oncology
ESMO
Medical Research Fellowship at Institut Jules Bordet
Novartis
Publisher
Elsevier BV
Subject
Oncology,Hematology
Link
http://academic.oup.com/annonc/article-pdf/30/Supplement_10/x27/31574988/mdz280.pdf
Reference71 articles.
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3. PIK3CA and AKT1 mutations have distinct effects on sensitivity to targeted pathway inhibitors in an isogenic luminal breast cancer model system;Beaver;Clin Cancer Res,2013
4. Predictive biomarkers of sensitivity to the phosphatidylinositol 3′ kinase inhibitor GDC-0941 in breast cancer preclinical models;O’Brien;Clin Cancer Res,2010
5. Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer;Schmid;J Clin Oncol,2016
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