Dynamic molecular analysis and clinical correlates of tumor evolution within a phase II trial of panitumumab-based therapy in metastatic colorectal cancer-Reference-Cited by-同舟云学术

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Dynamic molecular analysis and clinical correlates of tumor evolution within a phase II trial of panitumumab-based therapy in metastatic colorectal cancer

Published:2018-01 Issue:1 Volume:29 Page:119-126
ISSN:0923-7534
Container-title:Annals of Oncology
language:en
Short-container-title:Annals of Oncology

Author:

Siena S.,Sartore-Bianchi A.,Garcia-Carbonero R.,Karthaus M.,Smith D.,Tabernero J.,Van Cutsem E.,Guan X.,Boedigheimer M.,Ang A.,Twomey B.,Bach B.A.,Jung A.S.,Bardelli A.

Funder

European Community’s Seventh Framework Programme and H2020 Research and Innovation Programme

MErCuRIC

MoTriColor

MoTriColor European Union Horizon 2020 research and innovation programme

Publisher

Elsevier BV

Subject

Oncology,Hematology

Link

http://academic.oup.com/annonc/article-pdf/29/1/119/24170026/mdx504.pdf

Reference18 articles.

1. Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer;Douillard;N Engl J Med,2013

2. Resistance to anti-EGFR therapy in colorectal cancer: from heterogeneity to convergent evolution;Misale;Cancer Discov,2014

3. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers;Diaz;Nature,2012

4. Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer;Misale;Nature,2012

5. Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients;Siravegna;Nat Med,2015

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3. Unveiling acquired resistance to anti-EGFR therapies in colorectal cancer: a long and winding road;Frontiers in Pharmacology;2024-04-22

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