Systematic evaluation of pembrolizumab dosing in patients with advanced non-small-cell lung cancer

Author:

Chatterjee M.,Turner D.C.,Felip E.,Lena H.,Cappuzzo F.,Horn L.,Garon E.B.,Hui R.,Arkenau H.-T.,Gubens M.A.,Hellmann M.D.,Dong D.,Li C.,Mayawala K.,Freshwater T.,Ahamadi M.,Stone J.,Lubiniecki G.M.,Zhang J.,Im E.,De Alwis D.P.,Kondic A.G.,Fløtten Ø.

Funder

Merck & Co., Inc.

Publisher

Elsevier BV

Subject

Oncology,Hematology

Reference17 articles.

1. Population pharmacokinetics of therapeutic monoclonal antibodies;Dirks;Clin Pharmacokinet,2010

2. Population pharmacokinetic (popPK) model of pembrolizumab (pembo; MK-3475) in patients (pts) treated in KEYNOTE-001 and KEYNOTE-002;Gangadhar;J Clin Oncol,2015

3. Phase I study of pembrolizumab (MK-3475; anti-PD-1 monoclonal antibody) in patients with advanced solid tumors;Patnaik;Clin Cancer Res,2015

4. Pembrolizumab for the treatment of non-small-cell lung cancer;Garon;N Engl J Med,2015

5. Elucidation of relationship between tumor size and survival in non-small-cell lung cancer patients can aid early decision making in clinical drug development;Wang;Clin Pharmacol Ther,2009

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