Phase II study of the HSP90-inhibitor BIIB021 in gastrointestinal stromal tumors
Author:
Funder
Biogen Idec
Publisher
Elsevier BV
Subject
Oncology,Hematology
Link
http://academic.oup.com/annonc/article-pdf/24/1/252/13789235/mds275.pdf
Reference15 articles.
1. Gastrointestinal stromal tumour;Rubin;Lancet,2007
2. Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations;Wardelmann;Lancet Oncol,2005
3. Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor;Bauer;Cancer Res,2006
4. BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90;Lundgren;Mol Cancer Ther,2009
5. BIIB021, an oral, synthetic non-ansamycin Hsp90 inhibitor: Phase I experience;Elfiky;J Clin Oncol,2008
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