Assessment of nivolumab exposure and clinical safety of 480 mg every 4 weeks flat-dosing schedule in patients with cancer

Author:

Long G.V.,Tykodi S.S.,Schneider J.G.,Garbe C.,Gravis G.,Rashford M.,Agrawal S.,Grigoryeva E.,Bello A.,Roy A.,Rollin L.,Zhao X.

Funder

Bristol-Myers Squibb

Publisher

Elsevier BV

Subject

Oncology,Hematology

Reference19 articles.

1. OPDIVO (nivolumab) [package insert]. Princeton, NJ: Bristol-Myers Squibb; August 2018.

2. OPDIVO (nivolumab) [summary of product characteristics]. Uxbridge, UK: Bristol-Myers Squibb; July 2018.

3. Nivolumab dose selection: challenges, opportunities, and lessons learned for cancer immunotherapy;Agrawal;J Immunother Cancer,2016

4. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer;Topalian;N Engl J Med,2012

5. Model-based population pharmacokinetic analysis of nivolumab in patients with solid tumors;Bajaj;CPT Pharmacometrics Syst Pharmacol,2017

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