A phase II study of epigenetic therapy with hydralazine and magnesium valproate to overcome chemotherapy resistance in refractory solid tumors

Author:

Candelaria M.,Gallardo-Rincón D.,Arce C.,Cetina L.,Aguilar-Ponce J.L.,Arrieta Ó,González-Fierro A.,Chávez-Blanco A.,de la Cruz-Hernández E.,Camargo M.F.,Trejo-Becerril C.,Pérez-Cárdenas E.,Pérez-Plasencia C.,Taja-Chayeb L.,Wegman-Ostrosky T.,Revilla-Vazquez A.,Dueñas-González A.

Publisher

Elsevier BV

Subject

Oncology,Hematology

Reference42 articles.

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2. Can the state of cancer chemotherapy resistance be reverted by epigenetic therapy?;Pérez-Plasencia;Mol Cancer,2006

3. Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity;Cornacchia;J Immunol,1988

4. Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy;Segura-Pacheco;Clin Cancer Res,2003

5. Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2′-deoxycytidine;Chuang;Mol Cancer Ther,2005

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