Relationship between objective responses in phase I trialsand potential efficacy of non-specific cytotoxic investigational new drugs

Author:

Sekine I.,Yamamoto N.,Kunitoh H.,Ohe Y.,Tamura T.,Kodama T.,Saijo N.

Publisher

Elsevier BV

Subject

Oncology,Hematology

Reference7 articles.

1. Cancer: Principles and Practice of Oncology;Simon,2001

2. The phase II trial;Wittes;Cancer Treat Rep,1985

3. Clinical drug development: an analysis of phase II trials, 1970–1985;Marsoni;Cancer Treat Rep,1987

4. Therapeutic response in phase I trials of antineoplastic agents;Estey;Cancer Treat Rep,1986

5. Response rates, duration of response, and dose response effects in phase I studies of antineoplastics;Von Hoff;Invest New Drug,1991

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