PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients
Author:
Publisher
Elsevier BV
Subject
Oncology,Hematology
Link
http://academic.oup.com/annonc/article-pdf/20/1/84/307603/mdn541.pdf
Reference27 articles.
1. Cetuximab for treatment of colorectal cancer;Jonker;N Engl J Med,2007
2. PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients;Frattini;Br J Cancer,2007
3. KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab;Lièvre;J Clin Oncol,2008
4. Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry;Chung;J Clin Oncol,2005
5. Lack of usefulness of epidermal growth factor receptor expression determination for cetuximab therapy in patients with colorectal cancer;Hebbar;Anticancer Drugs,2006
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