Pharmacogenetics and pharmacokinetics of CNS penetration of efavirenz and its metabolites

Author:

Decloedt Eric H12,Sinxadi Phumla Z2,van Zyl Gert U3,Wiesner Lubbe2,Khoo Saye4,Joska John A5,Haas David W67,Maartens Gary2

Affiliation:

1. Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa

2. Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa

3. Division of Medical Virology, Faculty of Medicine and Health Sciences, Stellenbosch University and National Health Laboratory Service, Cape Town, South Africa

4. Institute of Translational Medicine, University of Liverpool and Royal Liverpool University Hospital, Liverpool, UK

5. Division of Neuropsychiatry, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa

6. Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA

7. Department of Internal Medicine, Meharry Medical College, Nashville, TN, USA

Funder

South African Medical Research Council

European and Developing Countries Clinical Trials

National Institute of Allergy and Infectious Diseases of the National Institutes of Health

National Institute of Child Health and Human Development

National Institute of Mental Health

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

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