A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease-Reference-Cited by-同舟云学术

A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease

Published:2012-12-07 Issue:5 Volume:22 Page:1039-1049
ISSN:1460-2083
Container-title:Human Molecular Genetics
language:en
Short-container-title:

Author:

Holmans Peter¹,Moskvina Valentina¹,Jones Lesley¹,Sharma Manu²³,Vedernikov Alexey¹,Buchel Finja⁴,Sadd Mohamad⁵,Bras Jose M.⁶,Bettella Francesco⁷,Nicolaou Nayia⁸,Simón-Sánchez Javier⁸,Mittag Florian⁴,Gibbs J. Raphael⁹⁶,Schulte Claudia²³,Durr Alexandra¹⁰¹¹,Guerreiro Rita⁶,Hernandez Dena⁹⁶,Brice Alexis¹⁰¹¹¹²¹³,Stefánsson Hreinn⁷,Majamaa Kari¹⁴,Gasser Thomas²³,Heutink Peter⁸,Wood Nicholas W.⁶¹⁵,Martinez Maria⁵,Singleton Andrew B.⁹,Nalls Michael A.⁹,Hardy John⁶,Morris Huw R.¹,Williams Nigel M.¹,Arepalli Sampath,Barker Roger,Barrett Jeffrey,Ben-Shlomo Yoav,Berendse Henk W.,Berg Daniela,Bhatia Kailash,de Bie Rob M.A.,Biffi Alessandro,Bloem Bas,Brice Alexis,Bochdanovits Zoltan,Bonin Michael,Bras Jose M.,Brockmann Kathrin,Brooks Janet,Burn David J.,Charlesworth Gavin,Chen Honglei,Chinnery Patrick F.,Chong Sean,Clarke Carl E.,Cookson Mark R.,Cooper Jonathan M.,Corvol Jen-Christophe,Counsell Carl,Damier Philippe,Dartigues Jean Francois,Deloukas Panagiotis,Deuschl Günther,Dexter David T.,van Dijk Karin D.,Dillman Allissa,Durif Frank,Durr Alexandra,Edkins Sarah,Evans Jonathan R.,Foltynie Thomas,Gao Jianjun,Gardner Michelle,Gasser Thomas,Gibbs J. Raphael,Goate Alison,Gray Emma,Guerreiro Rita,Gústafsson Ómar,Hardy John,Harris Clare,Hernandez Dena G.,Heutink Peter,van Hilten Jacobus J.,Hofman Albert,Hollenbeck Albert,Holmans Peter,Holton Janice,Hu Michele,Huber Heiko,Hudson Gavin,Hunt Sarah E.,Huttenlocher Johanna,Illig Thomas,Langford Cordelia,Lees Andrew,Lesage Suzanne,Lichtner Peter,Limousin Patricia,Lopez Grisel,Lorenz Delia,Martinez Maria,McNeill Alisdair,Moorby Catriona,Moore Matthew,Morris Huw,Morrison Karen E.,Moskvina Valentina,Mudanohwo Ese,Nalls Michael A.,Pearson Justin,Perlmutter Joel S.,Pétursson Hjörvar,Plagnol Vincent,Pollak Pierre,Post Bart,Potter Simon,Ravina Bernard,Revesz Tamas,Riess Olaf,Rivadeneira Fernando,Rizzu Patrizia,Ryten Mina,Saad Mohamad,Sawcer Stephen,Schapira Anthony,Scheffer Hans,Sharma Manu,Shaw Karen,Sheerin Una-Marie,Shoulson Ira,Schulte Claudia,Sidransky Ellen,Simón-Sánchez Javier,Singleton Andrew B.,Smith Colin,Stefánsson Hreinn,Stefánsson Kári,Steinberg Stacy,Stockton Joanna D.,Sveinbjornsdottir Sigurlaug,Talbot Kevin,Tanner Carlie M.,Tashakkori-Ghanbaria Avazeh,Tison François,Trabzuni Daniah,Traynor Bryan J.,Uitterlinden André G.,Velseboer Daan,Vidailhet Marie,Walker Robert,van de Warrenburg Bart,Wickremaratchi Mirdhu,Williams Nigel,Williams-Gray Caroline H.,Winder-Rhodes Sophie,Wood Nicholas,

Affiliation:

1. Department of Psychological Medicine and Neurology, Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre in Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK,

2. Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany,

3. DZNE – Deutsches Zentrum fur Neurodegenerative Erkrangungen (German Center for Neurodegenerative Diseases), Tuebingen, Germany,

4. Center for Bioinformatics Tuebingen (ZBIT) and

5. Paul Sabatier University, Toulouse, France,

6. Department of Molecular Neuroscience, Institute of Neurology and

7. deCODE genetics, Scientific Services, Sturlugata, 8 IS-101 Reykjavik, Iceland,

8. Section of Medical Genomics, Department of Clinical Genetics, VU University Medical Centre, Amsterdam, The Netherlands,

9. Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA,

10. Inserm, UMRS975, CNRS UMR 7225, CRICM, F-75013 Paris, France,

11. UPMC Univ Paris 06, UMRS975, F-75013, Paris, France,

12. AP-HP, Hôpital de la Salpêtrière, Département de Génétique, Paris, France,

13. Institut du Cerveau et de la Moelle Epinière, F-75013, Paris, France and

14. Department of Medical Biochemistry and Molecular Biology, FIN-90014 University of Oulu, Finland

15. UCL Genetics Institute, University College London, London, UK,

Publisher

Oxford University Press (OUP)

Subject

Genetics (clinical),Genetics,Molecular Biology,General Medicine

Link

http://academic.oup.com/hmg/article-pdf/22/5/1039/14140627/dds492.pdf

Reference47 articles.

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3. Incidence of Parkinson's disease: variation by age, gender, and race/ethnicity;Van Den Eeden;Am. J. Epidemiol.,2003

4. A common LRRK2 mutation in idiopathic Parkinson's disease;Gilks;Lancet,2005

5. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease;Polymeropoulos;Science,1997

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