IEDB-AR: immune epitope database—analysis resource in 2019-Reference-Cited by-同舟云学术

IEDB-AR: immune epitope database—analysis resource in 2019

Published:2019-05-22 Issue:W1 Volume:47 Page:W502-W506
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Dhanda Sandeep Kumar¹^ORCID,Mahajan Swapnil¹^ORCID,Paul Sinu¹,Yan Zhen¹,Kim Haeuk¹,Jespersen Martin Closter²,Jurtz Vanessa²,Andreatta Massimo²³^ORCID,Greenbaum Jason A¹,Marcatili Paolo²^ORCID,Sette Alessandro¹⁴,Nielsen Morten²³,Peters Bjoern¹⁴

Affiliation:

1. Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA

2. Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark

3. Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín, Argentina

4. Department of Medicine, University of California, San Diego, CA 92122, USA

Abstract

AbstractThe Immune Epitope Database Analysis Resource (IEDB-AR, http://tools.iedb.org/) is a companion website to the IEDB that provides computational tools focused on the prediction and analysis of B and T cell epitopes. All of the tools are freely available through the public website and many are also available through a REST API and/or a downloadable command-line tool. A virtual machine image of the entire site is also freely available for non-commercial use and contains most of the tools on the public site. Here, we describe the tools and functionalities that are available in the IEDB-AR, focusing on the 10 new tools that have been added since the last report in the 2012 NAR webserver edition. In addition, many of the tools that were already hosted on the site in 2012 have received updates to newest versions, including NetMHC, NetMHCpan, BepiPred and DiscoTope. Overall, this IEDB-AR update provides a substantial set of updated and novel features for epitope prediction and analysis.

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkz452/28684848/gkz452.pdf

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