In vivo pharmacodynamics of new-generation β-lactamase inhibitor taniborbactam (formerly VNRX-5133) in combination with cefepime against serine-β-lactamase-producing Gram-negative bacteria
Author:
Affiliation:
1. Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, CT, USA
2. Umm Al-Qura University, Makkah, Saudi Arabia
3. Division of Infectious Diseases, Hartford Hospital, Hartford, CT, USA
Abstract
Funder
Venatorx Pharmaceuticals, Inc.
National Institute of Allergy and Infectious Diseases
National Institutes of Health
Department of Health and Human Services
Wellcome Trust
Publisher
Oxford University Press (OUP)
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)
Link
http://academic.oup.com/jac/article-pdf/75/12/3601/34291468/dkaa373.pdf
Reference22 articles.
1. Past and present perspectives on β-lactamases;Bush;Antimicrob Agents Chemother,2018
2. VNRX-5133 (taniborbactam), a broad-spectrum inhibitor of serine- and metallo-β-lactamases, restores activity of cefepime in Enterobacterales and Pseudomonas aeruginosa;Hamrick;Antimicrob Agents Chemother,2020
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