Pneumocystis jirovecii pneumonia: still a concern in patients with haematological malignancies and stem cell transplant recipients

Author:

Cordonnier Catherine1,Cesaro Simone2,Maschmeyer Georg3,Einsele Hermann4,Donnelly J. Peter5,Alanio Alexandre6,Hauser Philippe M.7,Lagrou Katrien8,Melchers Willem J. G.9,Helweg-Larsen Jannik10,Matos Olga11,Bretagne Stéphane6,Maertens Johan12

Affiliation:

1. Department of Haematology, Henri Mondor Teaching Hospital, Assistance Publique-hôpitaux de Paris, and Université Paris-Est-Créteil, Créteil, France

2. Department of Haematology, Oncoematologia Pediatrica, Policlinico G. B. Rossi, Verona, Italy

3. Department of Haematology, Oncology and Palliative Care, Ernst-von-Bergmann Klinikum, Potsdam, Germany

4. Department of Internal Medicine II, Julius Maximilians University, Würzburg, Germany

5. Department of Haematology Radboud University Medical Center, Nijmegen, The Netherlands

6. Parasitology-Mycology Laboratory, Groupe Hospitalier Lariboisière Saint-Louis Fernand Widal, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris-Diderot, Sorbonne Paris Cité, and Institut Pasteur, Unité de Mycologie Moléculaire, CNRS URA3012, Centre National de Référence Mycoses Invasives et Antifongiques, Paris, France

7. Institute of Microbiology, Lausanne University Hospital and University, Lausanne, Switzerland

8. Department of Microbiology and Immunology, KU Leuven – University of Leuven, Leuven, Belgium and National Reference Center for Mycosis, Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium

9. Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands

10. Department of Infectious Diseases, Rigshospitalet-Copenhagen University Hospital, Copenhagen, Denmark

11. Medical Parasitology Unit, Group of Opportunistic Protozoa/HIV and Other Protozoa, Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisboa, Portugal

12. Department of Haematology, Acute Leukaemia and Stem Cell Transplantation Unit, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium

Abstract

The risk of patients with ALL and recipients of an allogeneic HSCT developing Pneumocystis jirovecii pneumonia is sufficiently high to warrant guidelines for the laboratory diagnosis, prevention and treatment of the disease. In this issue, the European Conference on Infections in Leukemia (ECIL) presents its recommendations in three companion papers.

Funder

Astellas Pharma, Gilead Sciences, Merck, and Pfizer

Basilea, Gilead Sciences, Merck, and Pfizer

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

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