1. Biostatistics and Research Decision Sciences, Merck & Co. , Inc., Rahway, NJ 07065, USA
2. Biostatistics and Research Decision Sciences, Merck & Co., Inc. , North Wales, PA 19454, USA
3. Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison , 330 N Orchard St, Madison, WI 53715, USA