Weathering the Storm: Managing Older Adults With Breast Cancer Amid COVID-19 and Beyond

Author:

Freedman Rachel A1ORCID,Sedrak Mina S2,Bellon Jennifer R3,Block Caroline C1,Lin Nancy U1,King Tari A4,Minami Christina4,VanderWalde Noam5,Jolly Trevor A6,Muss Hyman B6,Winer Eric P1

Affiliation:

1. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA

2. Department of Medical Oncology and Therapeutics Research, City of Hope, Duarte, CA, USA

3. Department of Radiation Oncology, Dana-Farber/Brigham and Women’s Cancer Center, Boston, MA, USA

4. Department of Surgery, Division of Breast Surgery, Brigham and Women’s Hospital, Boston, MA, USA

5. Department of Radiation Oncology, West Cancer Center and Research Institute, University of Tennessee Health Science Center, Memphis, TN, USA

6. Division of Hematology and Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27514, USA

Abstract

Abstract Caring for older patients with breast cancer presents unique clinical considerations because of preexisting and competing comorbidity, the potential for treatment-related toxicity, and the consequent impact on functional status. In the context of the COVID-19 pandemic, treatment decision making for older patients is especially challenging and encourages us to refocus our treatment priorities. While we work to avoid treatment delays and maintain therapeutic benefit, we also need to minimize the risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposures, myelosuppression, general chemotherapy toxicity, and functional decline. Herein, we propose multidisciplinary care considerations for the aging patient with breast cancer, with the goal to promote a team-based, multidisciplinary treatment approach during the COVID-19 pandemic and beyond. These considerations remain relevant as we navigate the “new normal” for the approximately 30% of breast cancer patients aged 70 years and older who are diagnosed in the United States annually and for the thousands of older patients living with recurrent and/or metastatic disease.

Funder

Susan G. Komen

American Cancer Society

National Cancer Institute

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

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