Leveraging national and global political determinants of health to promote equity in cancer care

Author:

Dee Edward Christopher1ORCID,Eala Michelle Ann B23ORCID,Robredo Janine Patricia G45,Ramiah Duvern6,Hubbard Anne7,Ho Frances Dominique V2,Sullivan Richard8,Aggarwal Ajay910,Booth Christopher M1112,Legaspi Gerardo D13,Nguyen Paul L14,Pramesh C S15,Grover Surbhi16

Affiliation:

1. Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York City , NY, USA

2. College of Medicine, University of the Philippines , Manila, Philippines

3. Department of Radiation Oncology, University of California, Los Angeles , Los Angeles, CA, USA

4. School of Medicine and Public Health, Ateneo de Manila University , Pasig City, Philippines

5. Blavatnik Institute of Global Health and Social Medicine, Harvard Medical School , Boston, MA, USA

6. Division of Radiation Oncology, University of the Witwatersrand, Johannesburg and Charlotte Maxeke Johannesburg Academic Hospital , Johannesburg, South Africa

7. American Society for Radiation Oncology , Arlington, VA, USA

8. Kings Health Partners Comprehensive Cancer Centre, King's College London, Institute of Cancer Policy , London, UK

9. Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine , London, UK

10. Clinical Effectiveness Unit, Institute of Cancer Policy, King’s College London , London, UK

11. Department of Oncology, Queen’s University , Kingston, ON, Canada

12. Cancer Care and Epidemiology, Cancer Research Institute, Queen’s University , Kingston, ON, Canada

13. Division of Neurosurgery, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila , Manila, Philippines

14. Department of Radiation Oncology, Dana-Farber Cancer Institute/Harvard Cancer Center , Boston, MA, USA

15. Tata Memorial Hospital, Thoracic Surgery (Surgical Oncology) at Tata Memorial Centre, Homi Bhabha National Institute , Mumbai, India

16. Department of Radiation Oncology, University of Pennsylvania , Philadelphia, PA, USA

Abstract

Abstract Health and politics are deeply intertwined. In the context of national and global cancer care delivery, political forces—the political determinants of health—influence every level of the cancer care continuum. We explore the “3-I” framework, which structures the upstream political forces that affect policy choices in the context of actors' interests, ideas, and institutions, to examine how political determinants of health underlie cancer disparities. Borrowing from the work of PA Hall, M-P Pomey, CJ Ho, and other thinkers, interests are the agendas of individuals and groups in power. Ideas represent beliefs or knowledge about what is or what should be. Institutions define the rules of play. We provide examples from around the world: Political interests have helped fuel the establishment of cancer centers in India and have galvanized the 2022 Cancer Moonshot in the United States. The politics of ideas underlie global disparities in cancer clinical trials—that is, in the distribution of epistemic power. Finally, historical institutions have helped perpetuate disparities related to racist and colonialist legacies. Present institutions have also been used to improve access for those in greatest need, as exemplified by the Butaro Cancer Center of Excellence in Rwanda. In providing these global examples, we demonstrate how interests, ideas, and institutions influence access to cancer care across the breadth of the cancer continuum. We argue that these forces can be leveraged to promote cancer care equity nationally and globally.

Funder

National Institutes of Health

National Cancer Institute

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

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