Influence of microbiota on immunity and immunotherapy for gastric and esophageal cancers-Reference-Cited by-同舟云学术

Influence of microbiota on immunity and immunotherapy for gastric and esophageal cancers

Published:2020-06-01 Issue:3 Volume:8 Page:206-214
ISSN:2052-0034
Container-title:Gastroenterology Report
language:en
Short-container-title:

Author:

Zhang Xiaoli¹,Pan Zui²^ORCID

Affiliation:

1. Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA

2. College of Nursing and Health Innovation, The University of Texas at Arlington, Arlington, TX, USA

Abstract

Abstract Gastric and esophageal cancers are multifactorial and multistage-involved malignancy. While the impact of gut microbiota on overall human health and diseases has been well documented, the influence of gastric and esophageal microbiota on gastric and esophageal cancers remains unclear. This review will discuss the reported alteration in the composition of gastric and esophageal microbiota in normal and disease conditions, and the potential role of dysbiosis in carcinogenesis and tumorigenesis. This review will also discuss how dysbiosis stimulates local and systemic immunity, which may impact on the immunotherapy for cancer.

Funder

Comprehensive Cancer Center Support

National Institutes of Health

National Cancer Institute

National Heart, Lung, and Blood Institute

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology

Link

http://academic.oup.com/gastro/article-pdf/8/3/206/33466212/goaa014.pdf

Reference96 articles.