Kidney diseases associated with Waldenström macroglobulinemia-Reference-Cited by-同舟云学术

Kidney diseases associated with Waldenström macroglobulinemia

Published:2018-10-31 Issue:10 Volume:34 Page:1644-1652
ISSN:0931-0509
Container-title:Nephrology Dialysis Transplantation
language:en
Short-container-title:

Author:

Uppal Nupur N¹,Monga Divya²,Vernace Melchiore A³,Mehtabdin Khurram¹,Shah Hitesh H¹,Bijol Vanesa⁴,Jhaveri Kenar D¹

Affiliation:

1. Division of Kidney Diseases and Hypertension, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA

2. Division of Nephrology, University of Mississippi Medical Center, Jackson, MS, USA

3. Nephrology-Hypertension Specialists, Doylestown, PA, USA

4. Department of Pathology, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA

Abstract

AbstractWaldenström macroglobulinemia (WM) is a rare B-cell lymphoma characterized by lymphoplasmacytic cell infiltration in the bone marrow and other organs and the presence of a monoclonal immunoglobulin M protein in the serum. Although uncommon, several kidney diseases have been associated with WM. In addition to kidney diseases related to lymphoplasmacytic lymphoma infiltration, a variety of glomerular and tubular lesions have been described in patients with WM. Immunoglobulin light chain (AL) amyloidosis and cryoglobulinemic glomerulonephritis are the two predominant glomerular pathologies seen in WM. In this article we review the kidney diseases associated with WM. We also briefly review some nephrotoxicities of novel chemotherapeutic and targeted therapies used for the treatment of WM.

Publisher

Oxford University Press (OUP)

Subject

Transplantation,Nephrology

Link

http://academic.oup.com/ndt/article-pdf/34/10/1644/30093868/gfy320.pdf

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