As-Needed Vs Immediate Etoposide Chemotherapy in Combination With Antiretroviral Therapy for Mild-to-Moderate AIDS-Associated Kaposi Sarcoma in Resource-Limited Settings: A5264/AMC-067 Randomized Clinical Trial

Author:

Hosseinipour Mina C12,Kang Minhee3,Krown Susan E4,Bukuru Aggrey5,Umbleja Triin3,Martin Jeffrey N6,Orem Jackson7,Godfrey Catherine8,Hoagland Brenda9,Mwelase Noluthando10,Langat Deborah11,Nyirenda Mulinda12,MacRae John13,Borok Margaret414,Samaneka Wadzanai14,Moses Agnes124,Mngqbisa Rosie15,Busakhala Naftali16,Martínez-Maza Otoniel417,Ambinder Richard418,Dittmer Dirk P24,Nokta Mostafa19,Campbell Thomas B20,

Affiliation:

1. UNC Project, Lilongwe, Malawi

2. University of North Carolina School of Medicine, Chapel Hill

3. Center for Biostatistics in AIDS Research, Harvard T.H. Chan School of Public Health, Boston, Massachusetts

4. AIDS Malignancy Consortium, New York, New York

5. Joint Clinical Research Center, Kampala, Uganda

6. University of California, San Francisco

7. Uganda Cancer Institute, Kampala

8. HIV Research Branch, TRP, DAIDS, NIAID, National Institutes of Health, Rockville, Maryland

9. INI Evandro Chagas/FIOCRUZ, Rio de Janiero, Brazil

10. University of Witwatersrand, Johannesburg, South Africa

11. Kenya Medical Research Institute/Walter Reed Project, Kericho

12. Johns Hopkins Project, University of Malawi College of Medicine, Blantyre, Malawi

13. IMPACTA Peru, Lima

14. University of Zimbabwe, Harare

15. DICRS, Enhancing Care Foundation, Durban, South Africa

16. Moi University, Eldoret, Kenya

17. University of California, Los Angeles

18. Johns Hopkins University, Baltimore

19. National Cancer Institute, Bethesda, Maryland

20. University of Colorado School of Medicine, Aurora

Funder

National Institutes of Health

National Cancer Institute

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Reference36 articles.

1. A cluster of Kaposi’s sarcoma and Pneumocystis carinii pneumonia among homosexual male residents of Los Angeles and Orange Counties, California;Centers for Disease Control;Morb Mortal Wkly Rep,1982

2. A prospective ascertainment of cancer incidence in sub-Saharan Africa: the case of Kaposi sarcoma;Semeere;Cancer Med,2016

3. Assessing the impact of HAART on the incidence of defining and non-defining AIDS cancers among patients with HIV/AIDS: a systematic review;Cobucci;J Infect Public Health,2015

4. Incidence rate of Kaposi sarcoma in HIV-infected patients on antiretroviral therapy in Southern Africa: a prospective multicohort study;Rohner;J Acquir Immune Defic Syndr,2014

5. Changing incidence and risk factors for Kaposi sarcoma by time since starting antiretroviral therapy: collaborative analysis of 21 European cohort studies;Cancer Project Working Group for the Collaboration of Observational HIV Epidemiological Research Europe Study in EuroCoord;Clin Infect Dis,2016

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