Lithium rescues toxicity of aggregate-prone proteins in Drosophila by perturbing Wnt pathway-Reference-Cited by-同舟云学术

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Lithium rescues toxicity of aggregate-prone proteins in Drosophila by perturbing Wnt pathway

Published:2005-09-02 Issue:20 Volume:14 Page:3003-3011
ISSN:1460-2083
Container-title:Human Molecular Genetics
language:en
Short-container-title:

Author:

Berger Zdenek,Ttofi Evangelia K.,Michel Claire H.,Pasco Matthieu Y.,Tenant Sean,Rubinsztein David C.,O'Kane Cahir J.

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

Link

http://academic.oup.com/hmg/article-pdf/14/20/3003/17241649/ddi331.pdf

Reference57 articles.

1. Gusella, J.F. and MacDonald, M.E. (2000) Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease. Nat. Rev. Neurosci., 1, 109–115.

2. Brown, L.Y. and Brown, S.A. (2004) Alanine tracts: the expanding story of human illness and trinucleotide repeats. Trends Genet., 20, 51–58.

3. Brais, B., Bouchard, J.P., Xie, Y.G., Rochefort, D.L., Chretien, N., Tome, F.M., Lafreniere, R.G., Rommens, J.M., Uyama, E., Nohira, O. et al. (1998) Short GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophy. Nat. Genet., 18, 164–167.

4. Carmichael, J., Sugars, K.L., Bao, Y.P. and Rubinsztein, D.C. (2002) Glycogen synthase kinase-3beta inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation. J. Biol. Chem., 277, 33791–33798.

5. Wood, N.I. and Morton, A.J. (2003) Chronic lithium chloride treatment has variable effects on motor behaviour and survival of mice transgenic for the Huntington's disease mutation. Brain Res. Bull., 61, 375–383.

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