Severe Neurological Sequelae after a Recreational Dose of LSD-Reference-Cited by-同舟云学术

Severe Neurological Sequelae after a Recreational Dose of LSD

Published:2020-10-08 Issue:7 Volume:45 Page:e1-e3
ISSN:0146-4760
Container-title:Journal of Analytical Toxicology
language:en
Short-container-title:

Author:

Aakerøy Rachel¹,Brede Wenche Rødseth¹,Stølen Stian Bergseng²,Krabseth Hege-Merete¹,Michelsen Lisbeth Solem¹,Andreassen Trine Naalsund¹,Ader Tiina³,Frost Joachim¹⁴,Slettom Grete⁵,Steihaug Ole Martin⁶,Slørdal Lars⁴¹

Affiliation:

1. Department of Clinical Pharmacology, St. Olav University Hospital, Trondheim, Norway

2. Department of Cardiology, St. Olav University Hospital, Trondheim, Norway

3. Department of Physical Medicine and Rehabilitation, Haukeland University Hospital, Bergen, Norway

4. Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway

5. Department of Heart Disease, Haukeland University Hospital, Bergen, Norway

6. Emergency Clinic, Haukeland University Hospital, Bergen, Norway

Abstract

Abstract A young man with an unremarkable medical history suffered a seizure with subsequent cardiorespiratory arrest and severe neurological sequelae after ingesting a blotter. Analysis of a similar blotter and a serum sample obtained 3 h after the event detected lysergic acid diethylamide (LSD) at an amount of 300 µg in the blotter and at a concentration of 4.0 ng/mL (12.4 nmol/L) in the serum. No other drugs were present in concentrations which may confer significant effects. In addition, no individual traits which would make the patient particularly susceptible to adverse LSD effects have subsequently been identified. This suggests that LSD may confer toxic effects in previously healthy individuals.

Publisher

Oxford University Press (OUP)

Subject

Chemical Health and Safety,Health, Toxicology and Mutagenesis,Toxicology,Environmental Chemistry,Analytical Chemistry

Link

http://academic.oup.com/jat/advance-article-pdf/doi/10.1093/jat/bkaa145/34248437/bkaa145.pdf

Reference11 articles.

1. Narkotika og dopingstatistikk;KRIPOS,2019

2. Is LSD toxic?;Nichols;Forensic Science International,2018

3. Neuropharmacology of N,N-dimethyltryptamine;Carbonaro;Brain Research Bulletin,2016

4. Impairment based legislative limits for driving under the influence of non-alcohol drugs in Norway;Vindenes;Forensic Science International,2012

5. The dark side of ecstasy: Neuropsychiatric symptoms after exposure to 3,4-methylenedioxymethamphetamine;Nyberg Karlsen;Basic and Clinical Pharmacology and Toxicology,2008

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The ambiguous relationship between food and health across the centuries;Clinical Nutrition ESPEN;2024-08

2. Psychedelics, epilepsy, and seizures: a review;Frontiers in Pharmacology;2024-01-12

3. Case report: Psychedelic-induced seizures captured by intracranial electrocorticography;Frontiers in Neurology;2023-06-29

4. Assessing the risk–benefit profile of classical psychedelics: a clinical review of second-wave psychedelic research;Psychopharmacology;2022-01-13

5. Psychedelic Psychiatry and the Consult-Liaison Psychiatrist: A Primer;Journal of the Academy of Consultation-Liaison Psychiatry;2021-07