DNA storage: research landscape and future prospects

Author:

Dong Yiming1ORCID,Sun Fajia1ORCID,Ping Zhi2ORCID,Ouyang Qi13ORCID,Qian Long1ORCID

Affiliation:

1. Center for Quantitative Biology and Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China

2. Academician Workstation of BGI Synthetic Genomics, BGI-Shenzhen, Shenzhen 518083, China

3. The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, School of Physics, Peking University, Beijing 100871, China

Abstract

Abstract The global demand for data storage is currently outpacing the world's storage capabilities. DNA, the carrier of natural genetic information, offers a stable, resource- and energy-efficient and sustainable data storage solution. In this review, we summarize the fundamental theory, research history, and technical challenges of DNA storage. From a quantitative perspective, we evaluate the prospect of DNA, and organic polymers in general, as a novel class of data storage medium.

Funder

National Natural Science Foundation of China

Ministry of Science and Technology of China

Guangdong Provincial Academician Workstation of BGI Synthetic Genomics

Publisher

Oxford University Press (OUP)

Subject

Multidisciplinary

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