1. From the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (EC, SEH, BR, WCW); the Departments of Epidemiology (SEH, BR, WCW), Biostatistics (BR), and Nutrition (EC and WCW), Harvard School of Public Health, Boston, MA; and the Department of Surgery and Alvin J Siteman Cancer Center, Washington University School of Medicine, St Louis,