Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses-Reference-Cited by-同舟云学术

Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses

Published:2017-07-01 Issue:7 Volume:30 Page:503-522
ISSN:1741-0126
Container-title:Protein Engineering, Design and Selection
language:en
Short-container-title:

Author:

Niyonzima Nixon¹,Lambert Abigail R.²,Werther Rachel²,De Silva Feelixge Harshana¹,Roychoudhury Pavitra¹^ORCID,Greninger Alexander L.¹³,Stone Daniel¹,Stoddard Barry L.²,Jerome Keith R.¹³

Affiliation:

1. Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA 98109, USA

2. Basic Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA 98109, USA

3. Virology Division, Department of Laboratory Medicine, University of Washington, 1616 Eastlake Ave. E, Seattle WA 98102, USA

Funder

National Institutes of Health

National Institute of General Medical Sciences

U.S. Department of Energy, Office of Basic Energy Sciences

Publisher

Oxford University Press (OUP)

Subject

Molecular Biology,Biochemistry,Bioengineering,Biotechnology

Link

http://academic.oup.com/peds/article-pdf/30/7/503/24351005/gzx037.pdf

Reference83 articles.

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4. Targeted DNA excision in Arabidopsis by a re-engineered homing endonuclease

5. The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

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