Extension of in vivo half-life of biologically active peptides via chemical conjugation to XTEN protein polymer-Reference-Cited by-同舟云学术

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Extension of in vivo half-life of biologically active peptides via chemical conjugation to XTEN protein polymer

Published:2013-10-16 Issue:11 Volume:26 Page:743-753
ISSN:1741-0126
Container-title:Protein Engineering Design and Selection
language:en
Short-container-title:Protein Engineering Design and Selection

Author:

Podust V. N.,Sim B.-C.,Kothari D.,Henthorn L.,Gu C.,Wang C.-w.,McLaughlin B.,Schellenberger V.

Publisher

Oxford University Press (OUP)

Subject

Molecular Biology,Biochemistry,Bioengineering,Biotechnology

Link

http://academic.oup.com/peds/article-pdf/26/11/743/4325673/gzt048.pdf

Reference23 articles.

1. GLP2-2G-XTEN: A Pharmaceutical Protein with Improved Serum Half-Life and Efficacy in a Rat Crohn’s Disease Model

2. Gas-Phase Proton-Transfer Chemistry Coupled with TOF Mass Spectrometry and Ion Mobility-MS for the Facile Analysis of Poly(ethylene glycols) and PEGylated Polypeptide Conjugates

3. PEG-modified biopharmaceuticals

4. Tunable Degradation of Maleimide–Thiol Adducts in Reducing Environments

5. Short Communication: Renal Tubular Vacuolation in Animals Treated with Polyethylene-Glycol-Conjugated Proteins

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