Modelling the human immune response: performance of a 1011 human antibody repertoire against a broad panel of therapeutically relevant antigens-Reference-Cited by-同舟云学术

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Modelling the human immune response: performance of a 1011 human antibody repertoire against a broad panel of therapeutically relevant antigens

Published:2008-10-16 Issue:3 Volume:22 Page:159-168
ISSN:1741-0126
Container-title:Protein Engineering Design and Selection
language:en
Short-container-title:Protein Engineering Design and Selection

Author:

Lloyd C.,Lowe D.,Edwards B.,Welsh F.,Dilks T.,Hardman C.,Vaughan T.

Publisher

Oxford University Press (OUP)

Subject

Molecular Biology,Biochemistry,Bioengineering,Biotechnology

Link

http://academic.oup.com/peds/article-pdf/22/3/159/4447283/gzn058.pdf

Reference26 articles.

1. A complete immunoglobulin gene is created by somatic recombination

2. Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells.

3. Potent antibody therapeutics by design

4. Heterogeneity of the peptide chains of γ-globulin

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