Lifespan developmental invariance in memory consolidation: evidence from procedural memory

Abstract

Abstract Characterizing ontogenetic changes across the lifespan is a crucial tool in understanding neurocognitive functions. While age-related changes in learning and memory functions have been extensively characterized in the past decades, the lifespan trajectory of memory consolidation, a critical function that supports the stabilization and long-term retention of memories, is still poorly understood. Here we focus on this fundamental cognitive function and probe the consolidation of procedural memories that underlie cognitive, motor, and social skills and automatic behaviors. We used a lifespan approach: 255 participants aged between 7 and 76 years performed a well-established procedural memory task in the same experimental design across the whole sample. This task enabled us to disentangle two critical processes in the procedural domain: statistical learning and general skill learning. The former is the ability to extract and learn predictable patterns of the environment, while the latter captures a general speed-up as learning progresses due to improved visuomotor coordination and other cognitive processes, independent of acquisition of the predictable patterns. To measure the consolidation of statistical and general skill knowledge, the task was administered in two sessions with a 24-h delay between them. Here, we report successful retention of statistical knowledge with no differences across age groups. For general skill knowledge, offline improvement was observed over the delay period, and the degree of this improvement was also comparable across the age groups. Overall, our findings reveal age invariance in these two key aspects of procedural memory consolidation across the human lifespan.