EyeHealer: A large-scale anterior eye segment dataset with eye structure and lesion annotations

Author:

Cai Wenjia1,Xu Jie2,Wang Ke3,Liu Xiaohong3,Xu Wenqin4,Cai Huimin4,Gao Yuanxu4,Su Yuandong5,Zhang Meixia5,Zhu Jie6,Zhang Charlotte L7,Zhang Edward E7,Wang Fangfei7,Yin Yun8,Lai Iat Fan9,Wang Guangyu10,Zhang Kang45,Zheng Yingfeng1

Affiliation:

1. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China

2. Beijing Institute of Ophthalmology, Capital Medical University, Beijing Tongren Hospital, Beijing 100730, China

3. Department of Computer Science and Technology & BNRist, Tsinghua University, Beijing 100084, China

4. Center for Biomedicine and Innovations, Faculty of Medicine, Macau University of Science and Technology and University Hospital, Macau 999078, China

5. Center for Translational Innovations, West China Hospital and Sichuan University, Chengdu 610041, China

6. Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China

7. Bioland Laboratory, Guangzhou 510005, China

8. School of Business, Macau University of Science and Technology, Macau 999078, China

9. Ophthalmic Center, Kiang Wu Hospital, Macau, China

10. School of Information and Communication Engineering, Beijing University of Posts and Telecommunications, Beijing 100876, China

Abstract

ABSTRACT Anterior segment eye diseases account for a significant proportion of presentations to eye clinics worldwide, including diseases associated with corneal pathologies, anterior chamber abnormalities (e.g. blood or inflammation), and lens diseases. The construction of an automatic tool for segmentation of anterior segment eye lesions would greatly improve the efficiency of clinical care. With research on artificial intelligence progressing in recent years, deep learning models have shown their superiority in image classification and segmentation. The training and evaluation of deep learning models should be based on a large amount of data annotated with expertise; however, such data are relatively scarce in the domain of medicine. Herein, the authors developed a new medical image annotation system, called EyeHealer. It is a large-scale anterior eye segment dataset with both eye structures and lesions annotated at the pixel level. Comprehensive experiments were conducted to verify its performance in disease classification and eye lesion segmentation. The results showed that semantic segmentation models outperformed medical segmentation models. This paper describes the establishment of the system for automated classification and segmentation tasks. The dataset will be made publicly available to encourage future research in this area.

Funder

National Key Research and Development Program of China

Leading Talents Program of Guangdong Province

Publisher

Oxford University Press (OUP)

Subject

General Medicine

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