Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer

Author:

Lindström Linda S1,Yau Christina23,Czene Kamila4,Thompson Carlie K2,Hoadley Katherine A5,van't Veer Laura J67,Balassanian Ron6,Bishop John W8,Carpenter Philip M910,Chen Yunn-Yi6,Datnow Brian11,Hasteh Farnaz11,Krings Gregor6,Lin Fritz10,Zhang Yanhong8,Nordenskjöld Bo12,Stål Olle12,Benz Christopher C23,Fornander Tommy13,Borowsky Alexander D8,Esserman Laura J2,

Affiliation:

1. Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden

2. Department of Surgery, University of California San Francisco, San Francisco, CA

3. Buck Institute for Research on Aging, Novato, CA

4. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

5. Department of Genetics, Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC

6. Department of Pathology, University of California San Francisco, San Francisco, CA

7. Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA

8. Center for Comparative Medicine, Department of Pathology and Laboratory Medicine, University of California Davis, Davis, CA

9. Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA

10. Department of Pathology and Laboratory Medicine, University of California Irvine, Irvine, CA

11. Department of Pathology and Laboratory Medicine, University of California San Diego, La Jolla, CA

12. Department of Clinical and Experimental Medicine and Department of Oncology, Linköping University, Linköping, Sweden

13. Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden

Funder

Swedish Research Council

FORTE

Swedish Cancer Society

Stockholm Cancer Society

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Reference36 articles.

1. Patterns of cancer incidence, mortality, and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world;Kamangar;J Clin Oncol.,2006

2. Prognostic value of steroid receptors after long-term follow-up of 2257 operable breast cancers;Pichon;Br J Cancer.,1996

3. Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: Patient-level meta-analysis of randomised trials;Early Breast Cancer Trialists' Collaborative Group;Lancet.,2011

4. Annual hazard rates of recurrence for breast cancer during 24 years of follow-up: Results from the International Breast Cancer Study Group trials I to V;Colleoni;J Clin Oncol.,2016

5. Frailty and adherence to adjuvant hormonal therapy in older women with breast cancer: CALGB protocol 369901;Sheppard;J Clin Oncol.,2014

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