Primitive Neuroectodermal Tumor in a Child with Human Immunodeficiency Virus Infection: A Rare Association

Author:

Gupta Aman1,Bhattarai Dharmagat1,Thapa Bishnu Kumar1,Parkhi Mayur2,Vignesh Pandiarajan1,Vasishta Rakesh K2,Tripathi Manjul3,Vyas Sameer4,Gupta Anju1

Affiliation:

1. Department of Pediatrics, Allergy Immunology Unit, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India

2. Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India

3. Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India

4. Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India

Abstract

Abstract Children with human immunodeficiency virus (HIV) infection are reported to have various malignancies, most common being Non-Hodgkin lymphoma. Despite higher risk of malignancies, brain tumors are infrequently described in these children. We report Primitive Neuroectodermal tumor (PNET) in a young boy with HIV infection. PNET has never been described in association with HIV infection. Though a causative association cannot be established, it does emphasize that with longer survivals on effective antiretroviral therapy, we may see a wide range of malignancies more frequently.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pediatrics, Perinatology and Child Health

Reference15 articles.

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3. Malignancies in children with Human Immunodeficiency Virus infection- our experience at Chandigarh, North India;Suri;J Trop Pediatr,2017

4. Children with cancer and HIV infection: what is different about them?;Stefan;J Pediatr Hematol Oncol,2013

5. Cerebral astrocytoma in association with HIV infection;Gasnault;J Neurol Neurosurg Psychiatry,1988

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