Scrub Typhus: A Spatial and Temporal Analysis from South India

Author:

Kumar Madhan1ORCID,Valiaveetil Koshy Alan1,Chandran Jolly1,Mohan Venkata Raghava2,Chandrasekar K3,Ghosh Urmi1ORCID,Punnen Anu1,Rose Winsley1

Affiliation:

1. Department of Paediatrics, Christian Medical College , Vellore, Tamil Nadu, India

2. Department of Community Health, Christian Medical College , Vellore, Tamil Nadu, India

3. Crop Parameter Retrieval Division, Agricultural Sciences Applications Group, National Remote Sensing Centre , Hyderabad, India

Abstract

Abstract Scrub typhus is a zoonotic rickettsial disease caused by the bacterium Orientia tsutsugamushi. The non-specificity of presentation, low index of suspicion and the poor availability of diagnostic tests often lead to delayed diagnosis and significant morbidity and mortality. Temperature, humidity, rainfall and Normalized Difference Vegetation Index (NDVI) on the spatio-temporal clustering of scrub typhus cases in children in three contiguous administrative districts in South India over 5 years were studied. A total of 419 children were diagnosed with scrub typhus during the study period. A surge of children with scrub typhus was noted when the NVDI ranged between 0.6 and 0.8 µm. Temperature, humidity and rainfall had a major role in the incidence of scrub typhus.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pediatrics, Perinatology and Child Health

Reference23 articles.

1. DHR-ICMR guidelines for diagnosis & management of rickettsial diseases in India;Rahi;Indian J Med Res,2015

2. Distribution of eschar in pediatric scrub typhus;Rose;J Trop Pediatr,2016

3. Scrub typhus and tropical rickettsioses;Watt;Curr Opin Infect Dis,2003

4. A systematic review of mortality from untreated scrub typhus (Orientia tsutsugamushi);Taylor;PLoS Negl Trop Dis,2015

5. Antibiotics for treating scrub typhus;Panpanich;Cochrane Database Syst Rev,2002

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