1. School of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, University of Southampton , Southampton SO16 6YD , United Kingdom
2. National Institute for Health and Care Research Applied Research Collaboration Wessex, University of Southampton , Southampton SO16 7NP , United Kingdom
3. Department of Hepatology, University Hospital Southampton NHS Trust , Southampton SO16 6YD , United Kingdom
4. National Institute for Health and Care Research Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Trust , Southampton SO16 6YD , United Kingdom
5. Academic Geriatric Medicine, Faculty of Medicine, University of Southampton , Southampton SO16 6YD , United Kingdom