Knowledge, opinions and attitudes of primary care physicians about generic drugs: a cross-sectional study

Author:

Oncu Seyma1,Bayram Dilara2,Aydin Volkan3,Isli Fatma4,Aksoy Mesil4,Akici Ahmet2,Ucku Reyhan5,Gelal Ayse1ORCID

Affiliation:

1. Department of Medical Pharmacology, Dokuz Eylul University School of Medicine, Izmir

2. Department of Medical Pharmacology, Marmara University School of Medicine, Istanbul

3. Department of Medical Pharmacology, International School of Medicine, Istanbul Medipol University, Istanbul

4. Turkish Medicines and Medical Devices Agency, Ministry of Health, Ankara

5. Department of Public Health, Dokuz Eylul University School of Medicine, Izmir, Turkey

Abstract

Abstract Background Generic drug (GD) use is affected by many factors, including physicians’ approach. Objective This study aimed to investigate the knowledge, opinions and attitudes of primary care physicians (PCPs) about GDs and potentially associated factors. Methods An adequately representative sample (n = 354) of PCPs was determined via stratified and simple random sample selection method in this descriptive, cross-sectional study. The research data were collected through a face-to-face 40-item survey, where the knowledge, opinions and attitudes about GDs were questioned. The prescribing percentage of GDs overall was also examined. Results The survey was completed by 305 PCPs (mean age: 49.2 ± 7.9 years; 57.4% male). The rate of correct responses about GDs was 67.6% for basic knowledge and 46.6% for the development process. The percentages of PCPs who declared that GDs were ‘less efficacious’, ‘of lower quality’ and ‘less safe’ than original drugs were 65.2%, 53.4% and 35.4%, respectively. More than half (60.3%) of the PCPs declared not to pay attention to whether the drug is generic while prescribing. It was observed that, as the knowledge level of the physicians increased, negative opinions and prescribing attitudes regarding the effectiveness, quality and safety of the GDs decreased. The rate of GD prescribing (51.6%) in Izmir was lower than the rest of the country (54.6%; P < 0.001). Conclusion This study shows that the knowledge of PCPs about GDs is generally inadequate, which reflects negatively on their opinions and attitudes regarding the use of GDs. Educational activities can help establish awareness that GDs can be used without doubt of their effectiveness, quality and safety.

Funder

Dokuz Eylul Universitesi Department of Scientific Research Projects

Publisher

Oxford University Press (OUP)

Subject

Family Practice

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