Immediate and substantial evolution of T-cell repertoire in peripheral blood and tumor microenvironment of patients with esophageal squamous cell carcinoma treated with preoperative chemotherapy

Author:

Zhang Chaoting1,Palashati Heyilimu1,Tan Qin2,Ku Wenjing1,Miao Yu3,Xiong Hongchao4,Lu Zheming1

Affiliation:

1. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Laboratory of Biochemistry and Molecular Biology

2. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Laboratory of Genetics, Peking University Cancer Hospital and Institute, Beijing, China

3. Research and Development Department, MyGenostics Inc., Beijing, China

4. Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Thoracic Surgery, Peking University Cancer Hospital and Institute, Beijing, China

Funder

Natural Science Foundation of Beijing Municipality

Beijing Municipal Science and Technology Commission

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,General Medicine

Reference40 articles.

1. Global cancer statistics, 2012;Torre;CA Cancer J. Clin,2015

2. Cancer statistics, 2018;Siegel;CA Cancer J. Clin,2018

3. Oesophageal carcinoma;Pennathur;Lancet,2013

4. Preoperative chemotherapy for resectable thoracic esophageal cancer;Kidane;Cochrane Database Syst. Rev,2015

5. Immunogenic chemotherapy sensitizes tumors to checkpoint blockade therapy;Pfirschke;Immunity,2016

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