Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G 2 /M arrest and multinucleation

Author:

Xie Yali,Yang Hanjing,Miller Jeffrey H.,Shih Diana M.,Hicks Geoffrey G.,Xie Jiuyong,Shiu Robert P.

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,General Medicine

Reference31 articles.

1. Oxidants, antioxidants, and the degenerative diseases of aging;Ames;Proc. Natl Acad. Sci. USA,1993

2. Increase of a type of oxidative DNA damage, 8-hydroxyguanine, and its repair activity in human leukocytes by cigarette smoking;Asami;Cancer Res.,1996

3. Cigarette smoking induces an increase in oxidative DNA damage, 8-hydroxydeoxyguanosine, in a central site of the human lung;Asami;Carcinogenesis,1997

4. Mammalian Ogg1/Mmh gene plays a major role in repair of the 8-hydroxyguanine lesion in DNA;Nishimura;Prog. Nucleic Acid Res. Mol. Biol.,2001

5. Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA;Michaels;Proc. Natl Acad. Sci. USA,1992

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