GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12

Author:

Tanikawa Chizu1,Kamatani Yoichiro2,Takahashi Atsushi23,Momozawa Yukihide4,Leveque Karine56,Nagayama Satoshi7,Mimori Koshi8,Mori Masaki9,Ishii Hideshi10,Inazawa Johji11,Yasuda Jun12,Tsuboi Akito12,Shimizu Atsushi13,Sasaki Makoto13,Yamaji Taiki14,Sawada Norie14,Iwasaki Motoki14,Tsugane Shoichiro15,Naito Mariko16,Wakai Kenji16,Koyama Teruhide17,Takezaki Toshiro18,Yuji Koichiro19,Murakami Yoshinori20,Nakamura Yusuke212223,Kubo Michiaki4,Matsuda Koichi15

Affiliation:

1. Laboratory of Genome Technology, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan

2. Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, RIKEN, Kanagawa, Japan

3. Department of Genomic Medicine, Research Institute, National Cerebral and Cardiovascular Center, Osaka, Japan

4. Laboratory for Genotyping Development, Center for Integrative Medical Sciences, RIKEN, Kanagawa, Japan

5. Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan

6. Oncology Master Progam, University Claude Bernard, Lyon I, Lyon, France

7. Department of Gastroenterology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan

8. Department of Surgery and Molecular Oncology, Medical Institute of Bioregulation, Kyushu University, Oita, Japan

9. Department of Gastroenterological Surgery and Graduate School of Medicine, Osaka University, Osaka, Japan

10. Department of Medical Data Science, Graduate School of Medicine, Osaka University, Osaka, Japan

11. Department of Molecular Cytogenetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan

12. Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan

13. Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan

14. Division of Epidemiology, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan

15. Center for Public Health Sciences, National Cancer Center, Tokyo, Japan

16. Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Aichi, Japan

17. Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan

18. Department of International Island and Community Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan

19. Project Division of International Advanced Medical Research, Institute of Medical Science, The University of Tokyo, Tokyo, Japan

20. Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan

21. Department of Medicine, The University of Chicago, IL, USA

22. Department of Surgery, The University of Chicago, IL, USA

23. Center for Personalized Therapeutics, The University of Chicago, IL, USA

Funder

Ministry of Education, Culture, Sports, Science and Technology

Japan Agency for Medical Research and Development

National Cancer Research and Development Fund

Ministry of Health, Labour and Welfare

Japan Ministry of Education, Science, Sports, Culture and Technology

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,General Medicine

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