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Aloe-emodin suppresses prostate cancer by targeting the mTOR complex 2

  • Published:2012-04-24 Issue:7 Volume:33 Page:1406-1411
  • ISSN:1460-2180
  • Container-title:Carcinogenesis
  • language:en
  • Short-container-title:

Author:

Liu Kangdong,Park Chanmi,Li Shengqing,Lee Ki Won,Liu Haidan,He Long,Soung Nak Kyun,Ahn Jong Seog,Bode Ann M.,Dong Ziming,Kim Bo Yeon,Dong Zigang

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,General Medicine

Reference34 articles.

1. The role of PTEN in the progression and survival of prostate cancer;Deocampo;Minerva Endocrinol.,2003

2. Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer;Gao;Biochem. Biophys. Res. Commun.,2003

3. PI3K signaling pathway is activated by PIK3CA mRNA overexpression and copy gain in prostate tumors, but PIK3CA, BRAF, KRAS and AKT1 mutations are infrequent events;Agell;Mod. Pathol,2011

4. Genetic alterations in the PI3K pathway in prostate cancer;Sun;Anticancer Res.,2009

5. Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state;Murillo;Endocrinology,2001
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