Telbivudine treatment corrects HBV-induced epigenetic alterations in liver cells of patients with chronic hepatitis B

Author:

Tian Yi,Ni Dongjing,Yang Weibing1,Zhang Yi,Zhao Keji2,Song Jianxun3,Mao Qing4,Tian Zhiqiang,van Velkinburgh Jennifer C.5,Yang Di,Wu Yuzhang,Ni Bing

Affiliation:

1. Department of Dermatology, the 181th Hospital of PLA, Guilin 541002, PR China,

2. Systems Biology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA,

3. Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA,

4. Department of Infectious Diseases, Southwestern Hospital, Third Military Medical University, Chongqing 400038, PR China and

5. van Velkinburgh Initiative for Collaboratory BioMedical Research, Santa Fe, NM 87501, USA

Funder

Major State Basic Research Development Program of China

Major Project of NSFC

Major Collaborative Project of NSFC

General Program of NSFC

Program for Changjiang Scholars and Innovative Research Team in University

Chongqing Science and Technology Commission

NIH

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,General Medicine

Reference37 articles.

1. Differential cellular gene expression induced by hepatitis B and C viruses;Otsuka;Biochem. Biophys. Res. Commun,(2003)

2. Differentially expressed cellular genes following HBV: potential targets of anti-HBV drugs?;Yang;J. Viral Hepat,(2005)

3. Hepatitis B virus X protein transactivates human interleukin-8 gene through acting on nuclear factor kB and CCAAT/enhancer-binding protein-like cis-elements;Mahé;J. Biol. Chem,(1991)

4. Interleukin 8 and MCAF: novel inflammatory cytokines inducible by IL 1 and TNF;Matsushima;Cytokine,(1989)

5. Hepatitis B virus sensitizes hepatocytes to complement-dependent cytotoxicity through downregulating CD59;Qu;Mol. Immunol,(2009)

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