Adductomic signatures of benzene exposure provide insights into cancer induction

Author:

Grigoryan Hasmik1,Edmands William M B1,Lan Qing2,Carlsson Henrik1,Vermeulen Roel3,Zhang Luoping1,Yin Song-Nian4,Li Gui-Lan4,Smith Martyn T1,Rothman Nathaniel2,Rappaport Stephen M1

Affiliation:

1. Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, USA

2. Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Service, Rockville, MD, USA

3. Division of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, TD Utrecht, The Netherlands

4. National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China

Funder

National Institutes of Health

National Cancer Institute

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,General Medicine

Reference44 articles.

1. Overall evaluations of carcinogenicity: an updating of IARC Monographs volumes 1 to 42;IARC;IARC Monogr Eval Carcinog Risks Hum Suppl,1987

2. Current understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessment;McHale;Carcinogenesis,2012

3. Benzene, the exposome and future investigations of leukemia etiology;Smith;Chem. Biol. Interact,2011

4. Albumin adducts of benzene oxide and 1,4-benzoquinone as measures of human benzene metabolism;Rappaport;Cancer Res,2002

5. Characterization and quantification of cysteinyl adducts of benzene diolepoxide;Waidyanatha;Chem. Res. Toxicol,2005

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